Clinical and In-Silico study of COVID?19 patients using Thymus capitatus extract as adjuvant Therapy
نویسندگان
چکیده
Thymus capitatus extract has been considered a promise as antiviral agent against COVID‑19 viruses. We hypothesized that components may interact with key protein targets of (coronavirus 2 (SARS-CoV-2) causing severe acute respiratory syndromes. Molecular docking analysis was carried out using 31 SARS-CoV-2 protease enzyme (6LU7) and spike glycoprotein (6VSB). The compounds the best normalized scores to were allo-Aromadendrene (-6.3 kcal/mole), spathulenol (-6.6 kcal/mole) ledene (-6.8 kcal/mole). ligands for (-7.3 All act synergistically produce therapeutic action. potentiate effect prednisolone, azithromycin other medicines used treat COVID-19 patients.
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ژورنال
عنوان ژورنال: International journal of clinical case reports and reviews
سال: 2021
ISSN: ['2690-4861']
DOI: https://doi.org/10.31579/2690-4861/102